A.V. Sakalo

Prognostic risk factors for relapse in clinical stage i managed by active surveillance

We aimed to analyze prognostic factors for relapse in stage I seminoma managed by active surveillance and to describe the long-term outcome and recurrences in nonselected group of patients. From 2005 to 2014 years a review of 76 unselected patients with histologically confirmed stage I seminoma who were threated by active surveillance was made. Prognostic risk factors for relapse were T classification, rete testis invasion.Options for postoperative treatment of stage I seminoma include radiotherapy, adjuvant chemotherapy and surveillance. With any of these options, practically all patients can be cured with salvage treatment at relapse. To provide the optimal outcome and minimizing the burden of treatment the risk-adapted management is promising.