I.M. Antonyan, M.L. Ugryumov, A.I. Zelenskyi, V.A. Goriacha, V.Y. Belov, Т.А. Nalbandian, F.G. Moshel

Prostate diseases. Diagnostic model and classification method

This publication contains the description of the joint study of two research groups - the physicians group and the statistics specialists group. The goal of the study was the improvement and stratification of diagnostic process in various prostate diseases. Application of contemporary mathematical analysis methods on clinical data allowed us to prove the possibility of differential diagnosis of different prostate conditions utilizing only one set of clinical data with a high probability degree. Moreover, this study gave the proof of opportunity to define the moment of transfer from hormone-sensitive into hormone-resistant prostate cancer. Statistically significant as well as statistically insignificant clinical indicators been identified for different prostate conditions. In addition, specific sets of clinical indicators been identified both for hormone-sensitive and hormone-resistant prostate cancers which gives the opportunity for adequate treatment options in the early stage of hormone-resistance.