V.M. Grygorenko, M.V. Vikarchuk, R.O. Danylets, O.O. Banas, N.V. Brovko, S.S. Volkov

Oncologic outcomes of radical prostatectomy in patients with clinical locally advanced prostate cancer

Oncologic outcomes of radical prostatectomy in 106 patients with clinically locally advanced prostate cancer were demonstrated. The mean patient’s age was 62,1 (40-78) years, mean PSA level - 29,4 (2,5-150) ng/ml. In pathological examination 17,9% of patients had localized prostate cancer, 19,8% - positive lymph nodes. Gleason Score was Ј 6 in 32 (30,2%), 7 - 47 (44,3%), і 8 - in 27 (25,5%) patients. Positive surgical margin were found in 37 (34,9%), perineural invasion of tumor - in 52 (49,1%) patients. The mean follow-up was 50, 6 (12-129) months. 5-year recurrence-free survival was 47,7%, 5-year cancer-specific and overall survival - 85,8%.