F.M. Wagenlehner

New antibiotics in the treatment of urinary tract infections

Antibiotics are very often prescribed for the indication urinary tract infections (UTIs). Therefore, UTIs are an important field for the development of antibiotic resistance. A number of new antibiotics have been tested for the indication complicated UTI / pyelonephritis. These are cephalosporins and carbapenems, in combination with new beta-lactamase inhibitors, cefiderocol as a new type of cephalosporin, plazomicin a new aminoglycoside, eravacycline a new tetracycline, and intravenous fosfomycin. Not all antibiotics are approved in Europe. Although the development of these new substances is promising, these new antibiotics should be used very carefully to avoid the development of new antibiotic resistance against these new substances.