K.A. Borisov, F.I. Kostev, A.V. Borisov
Changes in thiol status in patients with infravezical obstruction, provided comprehensive surgical treatment
The aim of our deep determination was the study of rational differential treatment strategy in patients with infravezical obstruction under the presence of bioenergy disorders in the body of patients in general and in the detrusor muscle of the bladder.
The obtained data on the changes in the blood of patients with thiol and disulfide groups of proteins, glutathione, and the activity level of enzymes glyutationovyh confirmed in the observed patient state of oxidative stress, which leads to impaired thiol status in biological fluids and tissues of the bladder, and allowed to reveal it important pathogenetic mechanisms.
In the article the clinical and laboratory description of 104 patient with the infravezical obstruction of different etiology, undervented a deep investigation in preparation for the surgical treatment presented. A conclusion about expedience of correction of glutathione status in complex surgical treatment of patients with infravezical obstruction was done.