M.K. Rokutova

The albumin and beta-2-microglobulin excretion in young patients with abdominal obesity, effects of cardiovascular risk factors

In the article the estimation results of the influence abdominal obesity and cardiovascular risk factors on urine albumin and urine beta -2-microglobulin in young persons with abdominal obesity are presented. 73 patients are inspected from age 18 by 40 with abdominal obesity, I-III (in obedience to classification of IDF, 2005). As a result of undertaken studies it is shown that this category of patients has high-frequency of basic cardiovascular risk factors: the positive inherited anamnesis on obesity and hypertension, mainly on a maternal line, smoking, hypertension 1 degree, impaired fasting glucose, impaired glucose tolerance, dyslipidemia, hyperinsulinemia, insulin resistance, and also hyperleptinemia. It is necessary to underline that reliable direct influence of abdominal obesity and associated metabolic displays on urine albumin and beta-2-microglobulin takes place. Thus, the necessity of exposure basic cardiovascular risk factors for the increase of diagnostics and treatment early obesity-association displays in this category of patients is shown.