V.P. Stus, K.S. Barannik, E.P. Ukrainian, N.V. Agafonov, N.V. Krasnov, V.V. Kostura, G.I. Martchenko, E.G. Olkchowskaya, N.V. Udovitchenko

Estimation of efficiency and safety силодозина in treatment of the symptom bottom uric ways at patients from good-quality hiperplazie prostate

Symptoms of the bottom uric ways against good-quality hiperplazie prostate represent a frequent problem at men of the senior age group and meet in 43 % of cases after 70 years. For elimination of the given symptoms used treatment by a preparation of Urorek (silodozine) in doses of 4 mg and 8 mg a day within 3 months. In research participated 131 patient with good-quality hiperplazie prostate. Age of patients from 48 to 91 years. Efficiency of action of a preparation on disease symptoms estimated on scale IPSS. Spent ultrasonic transabdominale research prostate before treatment. Simultaneously carried out monitoring of indicators of arterial pressure at all patients.

It is established that in 12 weeks of treatment decrease IPSS at patients who received a preparation in a dose of 8 mg with 18,9±1,8 points to 13±1,4 a point is marked. At patients who accepted a preparation in a dose of 4 mg a day, decrease in points has made from 16,9±1,0 to 11,0±0,8 (65 %). The volume of residual urine has decreased in 1 group for 56%, 2 - group for 44% . The By-effect in a kind retrograde eyaculation, directly correlated with decrease in symptoms of the bottom uric ways. The preparation did not render essential influence on a condition of arterial pressure at patients at all stages of treatment.

The conducted research has shown high enough efficiency of application of a preparation of Urorek (силодозина) for treatment of frustration мочеиспускания at patients with good-quality hiperplazie prostate.