V.P. Stus

Comparative analysis of the alpha-adrenoceptor antagonists for the treatment of BPH

The article presents a comparative study about the use of blockers in the treatment of lower urinary tract symptoms in benign prostatic hyperplasia.

According to Tatemishi S. at al. (2006) and Lepor H. (2009) silodozin is the most uroselective blocker among others.

Silodozin acts rapidly and it is the most effective a-blocker in reducing the most painful symptoms of lower urinary tract: noctury, feeling of incomplete emptying of the bladder and frequent urination. Taking into account that silodozin practicaly has no effect on the cardiovascular system, it can be recommended for patients who take phosphodiesterase-5 inhibitors and antihypertensive drugs.